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Verve Therapeutics
Cambridge, Massachusetts, United States
27 days ago
Amyris, Inc.
Remote, US
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Verve Therapeutics
Cambridge, Massachusetts, United States
27 days ago

Description

The Company

Verve Therapeutics is a biotechnology company created with a singular focus: to protect the world from heart disease. Founded by world-leading experts in cardiovascular medicine, human genetics, and gene editing, the company aims to develop transformative, once-and-done therapies for coronary heart disease. Verve’s gene-editing medicines are designed to safely edit the genome of adults and mimic naturally occurring gene variants to permanently lower LDL cholesterol and triglyceride levels. The company is advancing a pipeline of precision genetic medicines, led by VERVE-101, which is being developed initially for heterozygous familial hypercholesterolemia, a potentially fatal genetic heart disease. In 2020 and 2021, Verve was selected as a Best Places to Work by the Boston Business Journal and one of the Endpoints 11, which recognizes the most promising startups in biotech. Verve is headquartered in Cambridge, Massachusetts.

The Position

Verve is seeking a Senior Process Engineer to join a team developing an RNA encapsulated lipid nanoparticle gene-editing drug product. You will be involved across the development stages of lipid nanoparticle development. The successful candidate will be involved in product and process development and optimization, technology transfer of LNPs across sites, and scale-up activities. You will enable the development of a robust stable drug product in either a liquid or lyophilized presentation.

This role is flexible with respect to the level of experience and title.

  • The scientist/engineer in this position will be part of an integrated R&D team that aims to advance preclinical gene editing candidates through clinical development. This is a hands-on role with a high degree of independence.
  • The scientist/engineer will interact across teams to evaluate the impact of aseptic unit process operations on drug product integrity.
  • The successful candidate will be responsible for designing and executing studies that ensure successful technology transfer and scale-up.


Requirements

Requirements & Qualifications

  • Must have a degree in engineering, chemistry, biochemistry, pharmacy, or related area
  • Multiple years of relevant experience in drug development in an industry setting
  • Familiarity with regulatory submissions and strong technical writing skills are expected.
  • Experience with complex product process engineering for clinical applications is required.
  • Knowledge/hands-on experience in oligonucleotide lipid nanoparticle delivery is a plus.
  • Knowledge of various CRISPR-Cas9 based gene editing and/or base editing technologies is desirable but not expected.

EEO Statement
Verve Therapeutics is proud to be an equal opportunity workplace and is an affirmative action employer. We are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. If you have a disability or special need that requires accommodation, please let us know.

Recruitment & Staffing Agencies
Verve Therapeutics does not accept agency resumes unless contacted directly by internal Verve Talent Acquisition. Please do not forward resumes to Verve employees or any other company location; Verve Therapeutics is not responsible for any fees related to unsolicited resumes.

Job Information

  • Job ID: 57713995
  • Location:
    Cambridge, Massachusetts, United States
  • Position Title: Senior Process Engineer, Formulation & Characterization
  • Company Name: Verve Therapeutics
  • Job Function: Engineer,
    Formulation,
    Process Development
  • Job Type: Full-Time
  • Min Education: BA/BS/Undergraduate
  • Min Experience: 3-5 Years
  • Required Travel: None
Cambridge , MA ,

Verve is focused on discovering and developing therapies that safely edit the genomes of adults to confer protection against coronary artery disease, the most common type of heart disease and the leading cause of death worldwide. Verve brings together two of the biggest breakthroughs in 21st century biomedicine — human genetic analysis and gene editing — to realize a new future, one of longevity and vitality for tens of millions of people worldwide at risk of coronary artery disease.

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